Cytoplasmic amplification of transcriptional noise generates substantial cell-to-cell variability

Por Hansen, Maike M. K., Desai, Ravi V., Simpson, Michael L., Weinberger, Leor S.
Publicado no Cell Syst (2018)

Nonlatching positive feedback enables robust bimodality by decoupling expression noise from the mean

Por Razooky, Brandon S., Cao, Youfang, Hansen, Maike M. K., Perelson, Alan S., Simpson, Michael L., Weinberger, Leor S.
Publicado no PLoS Biol (2017)

Enhanced transcription rates in membrane-free protocells formed by coacervation of cell lysate

Por Sokolova, Ekaterina, Spruijt, Evan, Hansen, Maike M. K., Dubuc, Emilien, Groen, Joost, Chokkalingam, Venkatachalam, Piruska, Aigars, Heus, Hans A., Huck, Wilhelm T. S.
Publicado em 2013

Macromolecular crowding develops heterogeneous environments of gene expression in picoliter droplets

Por Hansen, Maike M. K., Meijer, Lenny H. H., Spruijt, Evan, Maas, Roel J. M., Roquelles, Marta Ventosa, Groen, Joost, Heus, Hans A., Huck, Wilhelm T. S.
Publicado no Nat Nanotechnol (2015)

A Post-Transcriptional Feedback Mechanism for Noise Suppression and Fate Stabilization

Por Hansen, Maike M. K., Wen, Winnie Y., Ingerman, Elena, Razooky, Brandon S., Thompson, Cassandra E., Dar, Roy D., Chin, Charles, Simpson, Michael L., Weinberger, Leor S.
Publicado no Cell (2018)