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Cell-to-cell transcript variability—seeing signal in the noise
How stochastic is gene expression in mammalian cells? Not very, according to Battich et al. (2015), who report that single-cell variability in cytoplasmic mRNAs is remarkably predictable given measurements of a cell’s phenotypic state and microenvironment. The noise from transcriptional bursts is bu...
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| 出版年: | Cell |
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| 第一著者: | |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4926623/ https://ncbi.nlm.nih.gov/pubmed/26687346 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.12.010 |
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