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Generation and Comparative Kinetic Analysis of New Glycosynthase Mutants from Streptococcus pyogenes Endoglycosidases for Antibody Glycoengineering

Chemoenzymatic glycan remodeling by endoglycosidase-catalyzed deglycosylation and reglycosylation is emerging as an attractive approach for producing homogeneous glycoforms of antibodies, and the success of this approach depends on the discovery of efficient endoglycosidases and their glycosynthase...

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Bibliografski detalji
Izdano u:Biochemistry
Glavni autori: Tong, Xin, Li, Tiezheng, Li, Chao, Wang, Lai-Xi
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6202118/
https://ncbi.nlm.nih.gov/pubmed/30102520
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.biochem.8b00719
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