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The role of tubulin-tubulin lattice contacts in the mechanism of microtubule dynamic instability
Microtubules form from longitudinally and laterally assembling tubulin α/β-dimers. The assembly induces strain in tubulin, resulting in cycles of microtubule catastrophe and regrowth. This so-called dynamic instability is governed by GTP hydrolysis that renders the microtubule lattice unstable, but...
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| Pubblicato in: | Nat Struct Mol Biol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2018
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6201834/ https://ncbi.nlm.nih.gov/pubmed/29967541 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41594-018-0087-8 |
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