Loading...
Impact of the Myosin Modulator Mavacamten on Force Generation and Cross‐Bridge Behavior in a Murine Model of Hypercontractility
BACKGROUND: Recent studies suggest that mavacamten (Myk461), a small myosin‐binding molecule, decreases hypercontractility in myocardium expressing hypertrophic cardiomyopathy‐causing missense mutations in myosin heavy chain. However, the predominant feature of most mutations in cardiac myosin bindi...
Na minha lista:
| Udgivet i: | J Am Heart Assoc |
|---|---|
| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2018
|
| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6201428/ https://ncbi.nlm.nih.gov/pubmed/30371160 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/JAHA.118.009627 |
| Tags: |
Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!
|