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β-adrenergic Regulation of Late Na(+) Current During Cardiac Action Potential Is Mediated by Both PKA and CaMKII
Late Na+ current (I(NaL)) significantly contributes to shaping cardiac action potentials (AP) and increased I(NaL) is associated with cardiac arrhythmias. β-adrenergic receptor (βAR) stimulation and its downstream signaling via protein kinase A (PKA) and Ca(2)+/calmodulin-dependent protein kinase II...
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| Publicado no: | J Mol Cell Cardiol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6201263/ https://ncbi.nlm.nih.gov/pubmed/30240676 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.yjmcc.2018.09.006 |
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