Investigating the Efficacy of Triple Artemisinin-Based Combination Therapies for Treating Plasmodium falciparum Malaria Patients Using Mathematical Modeling

The first line treatment for uncomplicated falciparum malaria is artemisinin-based combination therapy (ACT), which consists of an artemisinin derivative coadministered with a longer-acting partner drug. However, the spread of Plasmodium falciparum resistant to both artemisinin and its partner drugs...

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Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Dini, Saber, Zaloumis, Sophie, Cao, Pengxing, Price, Ric N., Fowkes, Freya J. I., van der Pluijm, Rob W., McCaw, James M., Simpson, Julie A.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2018
Schlagworte:
Analytical Procedures
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6201091/
https://ncbi.nlm.nih.gov/pubmed/30150462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01068-18
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