Development and Validation of an In Silico Decision Tool To Guide Optimization of Intravenous Artesunate Dosing Regimens for Severe Falciparum Malaria Patients

Most deaths from severe falciparum malaria occur within 24 h of presentation to a hospital. Intravenous (i.v.) artesunate is the first-line treatment for severe falciparum malaria, but its efficacy may be compromised by delayed parasitological responses. In patients with severe malaria, the life-sav...

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Dades bibliogràfiques
Publicat a:Antimicrob Agents Chemother
Autors principals: Zaloumis, Sophie G., Whyte, Jason M., Tarning, Joel, Krishna, Sanjeev, McCaw, James M., Cao, Pengxing, White, Michael T., Dini, Saber, Fowkes, Freya J. I., Maude, Richard J., Kremsner, Peter, Dondorp, Arjen, Price, Ric N., White, Nicholas J., Simpson, Julie A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2021
Matèries:
Clinical Therapeutics
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8316083/
https://ncbi.nlm.nih.gov/pubmed/33685888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02346-20
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