Population Pharmacokinetics of Intravenous Artesunate: A Pooled Analysis of Individual Data From Patients With Severe Malaria

There are ~660,000 deaths from severe malaria each year. Intravenous artesunate (i.v. ARS) is the first-line treatment in adults and children. To optimize the dosing regimen of i.v. ARS, the largest pooled population pharmacokinetic study to date of the active metabolite dihydroartemisinin (DHA) was...

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Detalhes bibliográficos
Publicado no:CPT Pharmacometrics Syst Pharmacol
Main Authors: Zaloumis, S G, Tarning, J, Krishna, S, Price, R N, White, N J, Davis, T M E, McCaw, J M, Olliaro, P, Maude, R J, Kremsner, P, Dondorp, A, Gomes, M, Barnes, K, Simpson, J A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2014
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4259998/
https://ncbi.nlm.nih.gov/pubmed/25372510
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/psp.2014.43
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