Population Pharmacokinetics of Intramuscular Artesunate in African Children With Severe Malaria: Implications for a Practical Dosing Regimen

Parenteral artesunate (ARS) is the drug of choice for the treatment of severe malaria. Pharmacokinetics data on intramuscular ARS are limited with respect to the main treatment group that carries the highest mortality, namely, critically ill children with severe malaria. A population pharmacokinetic...

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Detalhes bibliográficos
Main Authors: Hendriksen, ICE, Mtove, G, Kent, A, Gesase, S, Reyburn, H, Lemnge, M M, Lindegardh, N, Day, N P J, von Seidlein, L, White, N J, Dondorp, A M, Tarning, J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2013
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3630454/
https://ncbi.nlm.nih.gov/pubmed/23511715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/clpt.2013.26
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