In Silico Investigation of the Decline in Clinical Efficacy of Artemisinin Combination Therapies Due to Increasing Artemisinin and Partner Drug Resistance

Antimalarial treatment currently relies on an artemisinin derivative and a longer-acting partner drug. With the emergence of resistance to the artemisinin derivatives and the potential pressure this exerts on the partner drugs, the impact of resistance to each drug on efficacy needs to be investigat...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Antimicrob Agents Chemother
Egile Nagusiak: Zaloumis, Sophie G., Cao, Pengxing, Dini, Saber, Davenport, Miles P., Cromer, Deborah, Khoury, David S., Fowkes, Freya J. I., McCaw, James M., Simpson, Julie A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2018
Gaiak:
Mechanisms of Resistance
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6256805/
https://ncbi.nlm.nih.gov/pubmed/30249691
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01292-18
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