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Altered temporal response of malaria parasites determines differential sensitivity to artemisinin

Reports of emerging resistance to first-line artemisinin antimalarials make it critical to define resistance mechanisms and identify in vitro correlates of resistance. Here we combine unique in vitro experimental and analytical approaches to mimic in vivo drug exposure in an effort to provide insigh...

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Detalhes bibliográficos
Main Authors: Klonis, Nectarios, Xie, Stanley C., McCaw, James M., Crespo-Ortiz, Maria P., Zaloumis, Sophie G., Simpson, Julie A., Tilley, Leann
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3612604/
https://ncbi.nlm.nih.gov/pubmed/23431146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1217452110
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