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Haemoglobin degradation underpins the sensitivity of early ring stage Plasmodium falciparum to artemisinins

Current first-line artemisinin antimalarials are threatened by the emergence of resistant Plasmodium falciparum. Decreased sensitivity is evident in the initial (early ring) stage of intraerythrocytic development, meaning that it is crucial to understand the action of artemisinins at this stage. Her...

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Bibliografiske detaljer
Udgivet i:J Cell Sci
Main Authors: Xie, Stanley C., Dogovski, Con, Hanssen, Eric, Chiu, Francis, Yang, Tuo, Crespo, Maria P., Stafford, Che, Batinovic, Steven, Teguh, Silvia, Charman, Susan, Klonis, Nectarios, Tilley, Leann
Format: Artigo
Sprog:Inglês
Udgivet: The Company of Biologists Ltd 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732288/
https://ncbi.nlm.nih.gov/pubmed/26675237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.178830
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