Haemoglobin degradation underpins the sensitivity of early ring stage Plasmodium falciparum to artemisinins

Current first-line artemisinin antimalarials are threatened by the emergence of resistant Plasmodium falciparum. Decreased sensitivity is evident in the initial (early ring) stage of intraerythrocytic development, meaning that it is crucial to understand the action of artemisinins at this stage. Her...

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Detalhes bibliográficos
Publicado no:J Cell Sci
Main Authors: Xie, Stanley C., Dogovski, Con, Hanssen, Eric, Chiu, Francis, Yang, Tuo, Crespo, Maria P., Stafford, Che, Batinovic, Steven, Teguh, Silvia, Charman, Susan, Klonis, Nectarios, Tilley, Leann
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Ltd 2016
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732288/
https://ncbi.nlm.nih.gov/pubmed/26675237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.178830
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