Haemoglobin degradation underpins the sensitivity of early ring stage Plasmodium falciparum to artemisinins

Current first-line artemisinin antimalarials are threatened by the emergence of resistant Plasmodium falciparum. Decreased sensitivity is evident in the initial (early ring) stage of intraerythrocytic development, meaning that it is crucial to understand the action of artemisinins at this stage. Her...

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Veröffentlicht in:J Cell Sci
Hauptverfasser: Xie, Stanley C., Dogovski, Con, Hanssen, Eric, Chiu, Francis, Yang, Tuo, Crespo, Maria P., Stafford, Che, Batinovic, Steven, Teguh, Silvia, Charman, Susan, Klonis, Nectarios, Tilley, Leann
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Company of Biologists Ltd 2016
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4732288/
https://ncbi.nlm.nih.gov/pubmed/26675237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/jcs.178830
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