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Evaluation of pH during cytostomal endocytosis and vacuolar catabolism of haemoglobin in Plasmodium falciparum

The DV (digestive vacuole) of the malaria parasite, Plasmodium falciparum, is the site of Hb (haemoglobin) digestion and haem detoxification and, as a consequence, the site of action of CQ (chloroquine) and related antimalarials. However, the precise pH of the DV and the endocytic vesicles that feed...

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Detalhes bibliográficos
Main Authors: Klonis, Nectarios, Tan, Olivia, Jackson, Katherine, Goldberg, Daniel, Klemba, Michael, Tilley, Leann
Formato: Artigo
Idioma:Inglês
Publicado em: Portland Press Ltd. 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275073/
https://ncbi.nlm.nih.gov/pubmed/17696875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20070934
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