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Evaluation of pH during cytostomal endocytosis and vacuolar catabolism of haemoglobin in Plasmodium falciparum

The DV (digestive vacuole) of the malaria parasite, Plasmodium falciparum, is the site of Hb (haemoglobin) digestion and haem detoxification and, as a consequence, the site of action of CQ (chloroquine) and related antimalarials. However, the precise pH of the DV and the endocytic vesicles that feed...

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Détails bibliographiques
Auteurs principaux: Klonis, Nectarios, Tan, Olivia, Jackson, Katherine, Goldberg, Daniel, Klemba, Michael, Tilley, Leann
Format: Artigo
Langue:Inglês
Publié: Portland Press Ltd. 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2275073/
https://ncbi.nlm.nih.gov/pubmed/17696875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20070934
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