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Distribution and Biochemical Properties of an M1-family Aminopeptidase in Plasmodium falciparum Indicate a Role in Vacuolar Hemoglobin Catabolism

Aminopeptidases catalyze N-terminal peptide bond hydrolysis and occupy many diverse roles across all domains of life. Here we present evidence that an M1-family aminopeptidase, PfA-M1, has been recruited to specialized roles in the human malaria parasite Plasmodium falciparum. PfA-M1 is abundant in...

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Detalhes bibliográficos
Main Authors: Ragheb, Daniel, Dalal, Seema, Bompiani, Kristin M., Ray, W. Keith, Klemba, Michael
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149319/
https://ncbi.nlm.nih.gov/pubmed/21659511
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.225318
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