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Combination of immune checkpoint blockade with DNA cancer vaccine induces potent antitumor immunity against P815 mastocytoma

DNA vaccination against cancer has become a promising strategy for inducing a specific and long-lasting antitumor immunity. However, DNA vaccines fail to generate potent immune responses when used as a single therapy. To enhance their activity into the tumor, a DNA vaccine against murine P815 mastoc...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Lopes, Alessandra, Vanvarenberg, Kevin, Kos, Špela, Lucas, Sophie, Colau, Didier, Van den Eynde, Benoît, Préat, Véronique, Vandermeulen, Gaëlle
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2018
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6200811/
https://ncbi.nlm.nih.gov/pubmed/30356111
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33933-7
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