New generation of DNA-based immunotherapy induces a potent immune response and increases the survival in different tumor models

BACKGROUND: Strategies to increase nucleic acid vaccine immunogenicity are needed to move towards clinical applications in oncology. In this study, we designed a new generation of DNA vaccines, encoding an engineered vesicular stomatitis virus glycoprotein as a carrier of foreign T cell tumor epitop...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Immunother Cancer
Prif Awduron: Lopes, Alessandra, Bastiancich, Chiara, Bausart, Mathilde, Ligot, Sophie, Lambricht, Laure, Vanvarenberg, Kevin, Ucakar, Bernard, Gallez, Bernard, Préat, Véronique, Vandermeulen, Gaëlle
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: BMJ Publishing Group 2021
Pynciau:
Oncolytic and Local Immunotherapy
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC8021892/
https://ncbi.nlm.nih.gov/pubmed/33795383
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/jitc-2020-001243
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