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Fisetin targets YB-1/RSK axis independent of its effect on ERK signaling: insights from in vitro and in vivo melanoma models

The anti-proliferative activity of dietary flavonoid fisetin has been validated in various cancer models. Establishing its precise mechanism of action has proved somewhat challenging given the multiplicity of its targets. We demonstrated that YB-1 promotes epithelial-to-mesenchymal transition and it...

詳細記述

保存先:
書誌詳細
出版年:Sci Rep
主要な著者: Sechi, Mario, Lall, Rahul K., Afolabi, Saheed O, Singh, Anant, Joshi, Dinesh C., Chiu, Shing-Yan, Mukhtar, Hasan, Syed, Deeba N.
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6200766/
https://ncbi.nlm.nih.gov/pubmed/30356079
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-33879-w
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