Targeted therapy using nanotechnology: focus on cancer

Por Sanna, Vanna, Pala, Nicolino, Sechi, Mario
Publicado em 2014

Mechanisms underlying the cytotoxicity of a novel quinazolinedione-based redox modulator, QD232, in pancreatic cancer cells

Por Pathania, Divya, Kuang, Yuting, Sechi, Mario, Neamati, Nouri
Publicado no Br J Pharmacol (2015)

Nanoformulation of natural products for prevention and therapy of prostate cancer

Por Sanna, Vanna, Siddiqui, Imtiaz A., Sechi, Mario, Mukhtar, Hasan
Publicado em 2012

Resveratrol-Loaded Nanoparticles Based on Poly(epsilon-caprolactone) and Poly(d,l-lactic-co-glycolic acid)–Poly(ethylene glycol) Blend for Prostate Cancer Treatment

Por Sanna, Vanna, Siddiqui, Imtiaz Ahmad, Sechi, Mario, Mukhtar, Hasan
Publicado em 2013

Dietary flavonoid fisetin binds to β-tubulin and disrupts microtubule dynamics in prostate cancer cells

Por Mukhtar, Eiman, Adhami, Vaqar Mustafa, Sechi, Mario, Mukhtar, Hasan
Publicado no Cancer Lett (2015)

Mutational Analysis of the Binding Pockets of the Diketo Acid Inhibitor L-742,001 in the Influenza Virus PA Endonuclease

Por Stevaert, Annelies, Dallocchio, Roberto, Dessì, Alessandro, Pala, Nicolino, Rogolino, Dominga, Sechi, Mario, Naesens, Lieve
Publicado em 2013

Nanoencapsulation of natural triterpenoid celastrol for prostate cancer treatment

Por Sanna, Vanna, Chamcheu, Jean Christopher, Pala, Nicolino, Mukhtar, Hasan, Sechi, Mario, Siddiqui, Imtiaz Ahmad
Publicado no Int J Nanomedicine (2015)

Development of novel cationic chitosan-and anionic alginate–coated poly(d,l-lactide-co-glycolide) nanoparticles for controlled release and light protection of resveratrol

Por Sanna, Vanna, Roggio, Anna Maria, Siliani, Silvia, Piccinini, Massimo, Marceddu, Salvatore, Mariani, Alberto, Sechi, Mario
Publicado em 2012

Carbonic Anhydrase Inhibition with Benzenesulfonamides and Tetrafluorobenzenesulfonamides Obtained via Click Chemistry

Por Pala, Nicolino, Micheletto, Laura, Sechi, Mario, Aggarwal, Mayank, Carta, Fabrizio, McKenna, Robert, Supuran, Claudiu T.
Publicado em 2014

Virtual Screening and Biological Validation of Novel Influenza Virus PA Endonuclease Inhibitors

Por Pala, Nicolino, Stevaert, Annelies, Dallocchio, Roberto, Dessì, Alessandro, Rogolino, Dominga, Carcelli, Mauro, Sanna, Vanna, Sechi, Mario, Naesens, Lieve
Publicado no ACS Med Chem Lett (2015)

Fisetin inhibits human melanoma cell growth through direct binding to p70S6K and mTOR: findings from 3-D melanoma skin equivalents and computational modeling

Por Syed, Deeba N., Chamcheu, Jean-Christopher, Khan, Mohammad Imran, Sechi, Mario, Lall, Rahul K., Adhami, Vaqar M., Mukhtar, Hasan
Publicado em 2014

Single-step green synthesis and characterization of gold-conjugated polyphenol nanoparticles with antioxidant and biological activities

Por Sanna, Vanna, Pala, Nicolino, Dessì, Giuseppina, Manconi, Paola, Mariani, Alberto, Dedola, Sonia, Rassu, Mauro, Crosio, Claudia, Iaccarino, Ciro, Sechi, Mario
Publicado em 2014

N-acylhydrazone inhibitors of influenza virus PA endonuclease with versatile metal binding modes

Por Carcelli, Mauro, Rogolino, Dominga, Gatti, Anna, De Luca, Laura, Sechi, Mario, Kumar, Gyanendra, White, Stephen W., Stevaert, Annelies, Naesens, Lieve
Publicado no Sci Rep (2016)

Novel docetaxel-loaded nanoparticles based on poly(lactide-co-caprolactone) and poly(lactide-co-glycolide-co-caprolactone) for prostate cancer treatment: formulation, characterizat...

Por Sanna, Vanna, Roggio, Anna Maria, Posadino, Anna Maria, Cossu, Annalisa, Marceddu, Salvatore, Mariani, Alberto, Alzari, Valeria, Uzzau, Sergio, Pintus, Gianfranco, Sechi, Mario
Publicado em 2011

Inhibitory Effect of 2,3,5,6-Tetrafluoro-4-[4-(aryl)-1H-1,2,3-triazol-1-yl]benzenesulfonamide Derivatives on HIV Reverse Transcriptase Associated RNase H Activities

Por Pala, Nicolino, Esposito, Francesca, Rogolino, Dominga, Carcelli, Mauro, Sanna, Vanna, Palomba, Michele, Naesens, Lieve, Corona, Angela, Grandi, Nicole, Tramontano, Enzo, Sechi, Mario
Publicado no Int J Mol Sci (2016)

Targeted nanoparticles encapsulating (−)-epigallocatechin-3-gallate for prostate cancer prevention and therapy

Por Sanna, Vanna, Singh, Chandra K., Jashari, Rahime, Adhami, Vaqar M., Chamcheu, Jean Christopher, Rady, Islam, Sechi, Mario, Mukhtar, Hasan, Siddiqui, Imtiaz A.
Publicado no Sci Rep (2017)

YB-1 expression promotes epithelial-to-mesenchymal transition in prostate cancer that is inhibited by a small molecule fisetin

Por Khan, Mohammad Imran, Adhami, Vaqar Mustafa, Lall, Rahul Kumar, Sechi, Mario, Joshi, Dinesh C., Haidar, Omar M., Syed, Deeba Nadeem, Siddiqui, Imtiaz Ahmad, Chiu, Shing-Yan, Mukhtar, Hasan
Publicado em 2014

Ceftriaxone Blocks the Polymerization of α-Synuclein and Exerts Neuroprotective Effects in Vitro

Por Ruzza, Paolo, Siligardi, Giuliano, Hussain, Rohanah, Marchiani, Anna, Islami, Mehmet, Bubacco, Luigi, Delogu, Giovanna, Fabbri, Davide, Dettori, Maria A., Sechi, Mario, Pala, Nicolino, Spissu, Ylenia, Migheli, Rossana, Serra, Pier A., Sechi, GianPietro
Publicado em 2013

Dual Inhibition of PI3K/Akt and mTOR by the Dietary Antioxidant, Delphinidin, Ameliorates Psoriatic Features In Vitro and in an Imiquimod-Induced Psoriasis-Like Disease in Mice

Por Chamcheu, Jean Christopher, Adhami, Vaqar M., Esnault, Stephane, Sechi, Mario, Siddiqui, Imtiaz A., Satyshur, Kenneth A., Syed, Deeba N., Dodwad, Shah-Jahan M., Chaves-Rodriquez, Maria-Ines, Longley, B. Jack, Wood, Gary S., Mukhtar, Hasan
Publicado no Antioxid Redox Signal (2017)