Nanoencapsulation of natural triterpenoid celastrol for prostate cancer treatment

Celastrol (CL), a triterpenoid extracted from the Chinese herb Tripterygium wilfordii, has recently attracted interest for its potential antitumor effects. However, unfavorable physicochemical and pharmacokinetics properties such as low solubility, poor bioavailability, and systemic toxicity, are li...

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Опубликовано в: :Int J Nanomedicine
Главные авторы: Sanna, Vanna, Chamcheu, Jean Christopher, Pala, Nicolino, Mukhtar, Hasan, Sechi, Mario, Siddiqui, Imtiaz Ahmad
Формат: Artigo
Язык:Inglês
Опубликовано: Dove Medical Press 2015
Предметы:
Original Research
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636169/
https://ncbi.nlm.nih.gov/pubmed/26586945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S93752
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