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Nanoencapsulation of natural triterpenoid celastrol for prostate cancer treatment

Celastrol (CL), a triterpenoid extracted from the Chinese herb Tripterygium wilfordii, has recently attracted interest for its potential antitumor effects. However, unfavorable physicochemical and pharmacokinetics properties such as low solubility, poor bioavailability, and systemic toxicity, are li...

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Detalles Bibliográficos
Publicado en:Int J Nanomedicine
Main Authors: Sanna, Vanna, Chamcheu, Jean Christopher, Pala, Nicolino, Mukhtar, Hasan, Sechi, Mario, Siddiqui, Imtiaz Ahmad
Formato: Artigo
Idioma:Inglês
Publicado: Dove Medical Press 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4636169/
https://ncbi.nlm.nih.gov/pubmed/26586945
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S93752
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