Fisetin inhibits human melanoma cell growth through direct binding to p70S6K and mTOR: findings from 3-D melanoma skin equivalents and computational modeling

The incidence of melanoma continues to rise. Inspite of treatment advances, the prognosis remains grim once the disease has metastasized, emphasizing the need to explore additional therapeutic strategies. One such approach is through the use of mechanism-based dietary intervention. We previously sho...

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Bibliographic Details
Main Authors: Syed, Deeba N., Chamcheu, Jean-Christopher, Khan, Mohammad Imran, Sechi, Mario, Lall, Rahul K., Adhami, Vaqar M., Mukhtar, Hasan
Format: Artigo
Language:Inglês
Published: 2014
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4116133/
https://ncbi.nlm.nih.gov/pubmed/24675012
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2014.03.007
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