Discovery of a Novel Microtubule Targeting Agent as an Adjuvant for Cancer Immunotherapy

For an activating immunotherapy such as adjuvants, a compound that can prolong immune stimulation may enhance efficacy. We leveraged data from two prior high throughput screens with NF-κB and interferon reporter cell lines to identify 4H-chromene-3-carbonitriles as a class of compounds that prolonge...

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Библиографические подробности
Опубликовано в: :Biomed Res Int
Главные авторы: Sato-Kaneko, Fumi, Wang, Xiaodong, Yao, Shiyin, Hosoya, Tadashi, Lao, Fitzgerald S., Messer, Karen, Pu, Minya, Shukla, Nikunj M., Cottam, Howard B., Chan, Michael, Carson, Dennis A., Corr, Maripat, Hayashi, Tomoko
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi 2018
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6199861/
https://ncbi.nlm.nih.gov/pubmed/30406141
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2018/8091283
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