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Advances in Engineered Human Liver Platforms for Drug Metabolism Studies
Metabolism in the liver often determines the overall clearance rates of many pharmaceuticals. Furthermore, induction or inhibition of the liver drug metabolism enzymes by perpetrator drugs can influence the metabolism of victim drugs (drug-drug interactions). Therefore, determining liver-drug intera...
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| Publicado no: | Drug Metab Dispos |
|---|---|
| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Pharmacology and Experimental Therapeutics
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6199629/ https://ncbi.nlm.nih.gov/pubmed/30135245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.118.083295 |
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