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Advances in Engineered Liver Models for Investigating Drug-Induced Liver Injury
Drug-induced liver injury (DILI) is a major cause of drug attrition. Testing drugs on human liver models is essential to mitigate the risk of clinical DILI since animal studies do not always suffice due to species-specific differences in liver pathways. While primary human hepatocytes (PHHs) can be...
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| Publicado no: | Biomed Res Int |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Hindawi Publishing Corporation
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5048025/ https://ncbi.nlm.nih.gov/pubmed/27725933 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2016/1829148 |
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