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Advances in Engineered Human Liver Platforms for Drug Metabolism Studies

Metabolism in the liver often determines the overall clearance rates of many pharmaceuticals. Furthermore, induction or inhibition of the liver drug metabolism enzymes by perpetrator drugs can influence the metabolism of victim drugs (drug-drug interactions). Therefore, determining liver-drug intera...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Drug Metab Dispos
मुख्य लेखकों: Underhill, Gregory H., Khetani, Salman R.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The American Society for Pharmacology and Experimental Therapeutics 2018
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6199629/
https://ncbi.nlm.nih.gov/pubmed/30135245
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/dmd.118.083295
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