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Copy Number Alterations in Tumor Genomes Deleting Antineoplastic Drug Targets Partially Compensated by Complementary Amplifications
Background/Aim: Genomic DNA copy number alterations (CNAs) are frequent in tumors and have been catalogued by The Cancer Genome Atlas project. Emergence of chemoresistance frequently renders drug therapies ineffective. Materials and Methods: We analyzed how CNAs recurrently found in the genomes of T...
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| Publicado no: | Cancer Genomics Proteomics |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Institute of Anticancer Research
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6199575/ https://ncbi.nlm.nih.gov/pubmed/30194077 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21873/cgp.20095 |
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