Alteration of the copy number and deletion of mitochondrial DNA in human hepatocellular carcinoma

Somatic mutations in mitochondrial DNA (mtDNA) have been detected in hepatocellular carcinoma (HCC). However, it remains unclear whether mtDNA copy number and mitochondrial biogenesis are altered in HCC. In this study, we found that mtDNA copy number and the content of mitochondrial respiratory prot...

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Detalhes bibliográficos
Main Authors: Yin, P H, Lee, H C, Chau, G Y, Wu, Y T, Li, S H, Lui, W Y, Wei, Y H, Liu, T Y, Chi, C W
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2004
Assuntos:
Genetics and Genomics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409531/
https://ncbi.nlm.nih.gov/pubmed/15150555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601838
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