Alteration of the copy number and deletion of mitochondrial DNA in human hepatocellular carcinoma

Somatic mutations in mitochondrial DNA (mtDNA) have been detected in hepatocellular carcinoma (HCC). However, it remains unclear whether mtDNA copy number and mitochondrial biogenesis are altered in HCC. In this study, we found that mtDNA copy number and the content of mitochondrial respiratory prot...

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Hlavní autoři: Yin, P H, Lee, H C, Chau, G Y, Wu, Y T, Li, S H, Lui, W Y, Wei, Y H, Liu, T Y, Chi, C W
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2004
Témata:
Genetics and Genomics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409531/
https://ncbi.nlm.nih.gov/pubmed/15150555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601838
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