Alteration of the copy number and deletion of mitochondrial DNA in human hepatocellular carcinoma

Somatic mutations in mitochondrial DNA (mtDNA) have been detected in hepatocellular carcinoma (HCC). However, it remains unclear whether mtDNA copy number and mitochondrial biogenesis are altered in HCC. In this study, we found that mtDNA copy number and the content of mitochondrial respiratory prot...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Yin, P H, Lee, H C, Chau, G Y, Wu, Y T, Li, S H, Lui, W Y, Wei, Y H, Liu, T Y, Chi, C W
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2004
Schlagworte:
Genetics and Genomics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2409531/
https://ncbi.nlm.nih.gov/pubmed/15150555
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6601838
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