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Comparing copy-number profiles under multi-copy amplifications and deletions

BACKGROUND: During cancer progression, malignant cells accumulate somatic mutations that can lead to genetic aberrations. In particular, evolutionary events akin to segmental duplications or deletions can alter the copy-number profile (CNP) of a set of genes in a genome. Our aim is to compute the ev...

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Detalhes bibliográficos
Publicado no:BMC Genomics
Main Authors: Cordonnier, Garance, Lafond, Manuel
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7160889/
https://ncbi.nlm.nih.gov/pubmed/32299350
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-020-6611-3
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