Decreased mitochondrial respiration in aneurysmal aortas of Fibulin-4 mutant mice is linked to PGC1A regulation

AIM: Thoracic aortic aneurysms are a life-threatening condition often diagnosed too late. To discover novel robust biomarkers, we aimed to better understand the molecular mechanisms underlying aneurysm formation. METHODS AND RESULTS: In Fibulin-4(R/R) mice, the extracellular matrix protein Fibulin-4...

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出版年:Cardiovasc Res
主要な著者: van der Pluijm, Ingrid, Burger, Joyce, van Heijningen, Paula M, IJpma, Arne, van Vliet, Nicole, Milanese, Chiara, Schoonderwoerd, Kees, Sluiter, Willem, Ringuette, Lea-Jeanne, Dekkers, Dirk H W, Que, Ivo, Kaijzel, Erik L, te Riet, Luuk, MacFarlane, Elena G, Das, Devashish, van der Linden, Reinier, Vermeij, Marcel, Demmers, Jeroen A, Mastroberardino, Pier G, Davis, Elaine C, Yanagisawa, Hiromi, Dietz, Harry C, Kanaar, Roland, Essers, Jeroen
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2018
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Original Articles
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6198735/
https://ncbi.nlm.nih.gov/pubmed/29931197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvy150
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