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Structure of the human epithelial sodium channel by cryo-electron microscopy
The epithelial sodium channel (ENaC), a member of the ENaC/DEG superfamily, regulates Na(+) and water homeostasis. ENaCs assemble as heterotrimeric channels that harbor protease-sensitive domains critical for gating the channel. Here, we present the structure of human ENaC in the uncleaved state det...
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| Publicado en: | eLife |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
eLife Sciences Publications, Ltd
2018
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6197857/ https://ncbi.nlm.nih.gov/pubmed/30251954 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.39340 |
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