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Centromeres License the Mitotic Condensation of Yeast Chromosome Arms

During mitosis, chromatin condensation shapes chromosomes as separate, rigid, and compact sister chromatids to facilitate their segregation. Here, we show that, unlike wild-type yeast chromosomes, non-chromosomal DNA circles and chromosomes lacking a centromere fail to condense during mitosis. The c...

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Detalles Bibliográficos
Publicado en:Cell
Main Authors: Kruitwagen, Tom, Chymkowitch, Pierre, Denoth-Lippuner, Annina, Enserink, Jorrit, Barral, Yves
Formato: Artigo
Idioma:Inglês
Publicado: Cell Press 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6197839/
https://ncbi.nlm.nih.gov/pubmed/30318142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.09.012
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