Centromeres License the Mitotic Condensation of Yeast Chromosome Arms

During mitosis, chromatin condensation shapes chromosomes as separate, rigid, and compact sister chromatids to facilitate their segregation. Here, we show that, unlike wild-type yeast chromosomes, non-chromosomal DNA circles and chromosomes lacking a centromere fail to condense during mitosis. The c...

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Bibliografske podrobnosti
izdano v:Cell
Main Authors: Kruitwagen, Tom, Chymkowitch, Pierre, Denoth-Lippuner, Annina, Enserink, Jorrit, Barral, Yves
Format: Artigo
Jezik:Inglês
Izdano: Cell Press 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6197839/
https://ncbi.nlm.nih.gov/pubmed/30318142
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2018.09.012
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