The ReFRAME library as a comprehensive drug repurposing library and its application to the treatment of cryptosporidiosis

The chemical diversity and known safety profiles of drugs previously tested in humans make them a valuable set of compounds to explore potential therapeutic utility in indications outside those originally targeted, especially neglected tropical diseases. This practice of “drug repurposing” has becom...

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Dades bibliogràfiques
Publicat a:Proc Natl Acad Sci U S A
Autors principals: Janes, Jeff, Young, Megan E., Chen, Emily, Rogers, Nicole H., Burgstaller-Muehlbacher, Sebastian, Hughes, Laura D., Love, Melissa S., Hull, Mitchell V., Kuhen, Kelli L., Woods, Ashley K., Joseph, Sean B., Petrassi, H. Michael, McNamara, Case W., Tremblay, Matthew S., Su, Andrew I., Schultz, Peter G., Chatterjee, Arnab K.
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2018
Matèries:
Biological Sciences
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6196526/
https://ncbi.nlm.nih.gov/pubmed/30282735
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1810137115
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