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Disrupting USP5/Cav3.2 interactions protects female mice from mechanical hypersensitivity during peripheral inflammation

Cav3.2 T-type calcium channels are important for the signaling of nociceptive information in the primary afferent pain pathway. During neuropathy and peripheral inflammation, Cav3.2 channels are upregulated due to an increased association with the deubiquitinase USP5. Disrupting these interactions i...

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Bibliografiske detaljer
Udgivet i:Mol Brain
Main Authors: Gadotti, Vinicius M., Zamponi, Gerald W.
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6194615/
https://ncbi.nlm.nih.gov/pubmed/30340616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-018-0405-4
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