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Disrupting USP5/Cav3.2 interactions protects female mice from mechanical hypersensitivity during peripheral inflammation

Cav3.2 T-type calcium channels are important for the signaling of nociceptive information in the primary afferent pain pathway. During neuropathy and peripheral inflammation, Cav3.2 channels are upregulated due to an increased association with the deubiquitinase USP5. Disrupting these interactions i...

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書目詳細資料
發表在:Mol Brain
Main Authors: Gadotti, Vinicius M., Zamponi, Gerald W.
格式: Artigo
語言:Inglês
出版: BioMed Central 2018
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6194615/
https://ncbi.nlm.nih.gov/pubmed/30340616
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13041-018-0405-4
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