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Molecular Imaging of Radiolabeled Bispecific T-cell Engager (89)Zr-AMG211 Targeting CEA-positive Tumors
BACKGROUND: AMG 211, a bispecific T-cell engager (BiTE) antibody construct, targets carcinoembryonic antigen (CEA) and the CD3 epsilon subunit of the human T-cell receptor. AMG 211 was labeled with zirconium-89 ((89)Zr) or fluorescent dye to evaluate the tumor targeting properties. EXPERIMENTAL DESI...
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| 出版年: | Clin Cancer Res |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6193542/ https://ncbi.nlm.nih.gov/pubmed/29980531 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-18-0786 |
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