(89)Zr-Onartuzumab PET imaging of c-MET receptor dynamics

PURPOSE: c-MET and its ligand hepatocyte growth factor are often dysregulated in human cancers. Dynamic changes in c-MET expression occur and might predict drug efficacy or emergence of resistance. Noninvasive visualization of c-MET dynamics could therefore potentially guide c-MET-directed therapies...

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Publicat a:Eur J Nucl Med Mol Imaging
Autors principals: Pool, Martin, Terwisscha van Scheltinga, Anton G. T., Kol, Arjan, Giesen, Danique, de Vries, Elisabeth G. E., Lub-de Hooge, Marjolijn N.
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2017
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Original Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5486818/
https://ncbi.nlm.nih.gov/pubmed/28315949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00259-017-3672-x
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