Plasma metabolomic profiling of a ketamine and placebo crossover trial of major depressive disorder and healthy control subjects

(R,S)-Ketamine produces rapid, robust, and sustained antidepressant effects in major depressive disorder. Specifically, its pharmacological efficacy in treatment refractory depression is considered a major breakthrough in the field. However, the mechanism of action of ketamine’s rapid effect remains...

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Vydáno v:Psychopharmacology (Berl)
Hlavní autoři: Moaddel, Ruin, Shardell, Michelle, Khadeer, Mohammed, Lovett, Jacqueline, Kadriu, Bashkim, Ravichandran, Sarangan, Morris, Patrick J., Yuan, Peixiong, Thomas, Craig J., Gould, Todd D., Ferrucci, Luigi, Zarate, Carlos A.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2018
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6193489/
https://ncbi.nlm.nih.gov/pubmed/30116859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-018-4992-7
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