Ketamine metabolites, clinical response, and gamma power in a randomized, placebo-controlled, crossover trial for treatment-resistant major depression

A single, subanesthetic dose of (R,S)-ketamine (ketamine) exerts rapid and robust antidepressant effects. Several groups previously reported that (2S,6S;2R,6R)-hydroxynorketamine (HNK) had antidepressant effects in rodents, and that (2R,6R)-HNK increased cortical electroencephalographic gamma power....

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Neuropsychopharmacology
मुख्य लेखकों: Farmer, Cristan A., Gilbert, Jessica R., Moaddel, Ruin, George, Jomy, Adeojo, Lilian, Lovett, Jacqueline, Nugent, Allison C., Kadriu, Bashkim, Yuan, Peixiong, Gould, Todd D., Park, Lawrence T., Zarate, Carlos A.
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Springer International Publishing 2020
विषय:
Article
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC7297997/
https://ncbi.nlm.nih.gov/pubmed/32252062
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41386-020-0663-6
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