Extracellular vesicles released by cardiomyocytes in a doxorubicin-induced cardiac injury mouse model contain protein biomarkers of early cardiac injury

PURPOSE: Cardiac injury is a major cause of death in cancer survivors, and biomarkers for it are detectable only after tissue injury has occurred. Extracellular vesicles (EVs) remove toxic biomolecules from tissues and can be detected in the blood. Here, we evaluate the potential of using circulatin...

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Publicat a:Clin Cancer Res
Autors principals: Yarana, Chontida, Carroll, Dustin, Chen, Jing, Chaiswing, Luksana, Zhao, Yanming, Noel, Teresa, Alstott, Michael, Bae, Younsoo, Dressler, Emily V., Moscow, Jeffrey A., Butterfield, D. Allan, Zhu, Haining, St. Clair, Daret K.
Format: Artigo
Idioma:Inglês
Publicat: 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6193451/
https://ncbi.nlm.nih.gov/pubmed/29070527
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-2046
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