Extracellular vesicle-mediated macrophage activation: An insight into the mechanism of thioredoxin-mediated immune activation

Extracellular vesicles (EVs) generated from redox active anticancer drugs are released into the extracellular environment. These EVs contain oxidized molecules and trigger inflammatory responses by macrophages. Using a mouse model of doxorubicin (DOX)-induced tissue injury, we previously found that...

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Bibliographic Details
Published in:Redox Biol
Main Authors: Yarana, Chontida, Thompson, Hannah, Chaiswing, Luksana, Butterfield, D. Allan, Weiss, Heidi, Bondada, Subbarao, Alhakeem, Sara, Sukati, Suriyan, St. Clair, Daret K.
Format: Artigo
Language:Inglês
Published: Elsevier 2019
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6612011/
https://ncbi.nlm.nih.gov/pubmed/31276937
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101237
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