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FBXW7 regulates a mitochondrial transcription program by modulating MITF

FBXW7 is well characterized as a tumor suppressor in many human cancers including melanoma; however, the mechanisms of tumor suppressive function have not been fully elucidated. We leveraged two distinct RNA sequencing datasets: human melanoma cell lines (n=10) with control versus silenced FBXW7 and...

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Detalhes bibliográficos
Publicado no:Pigment Cell Melanoma Res
Main Authors: Abbate, Franco, Badal, Brateil, Mendelson, Karen, Aydin, Iraz Toprak, Serasinghe, Madhavika N., Iqbal, Ramiz, Mohammed, Jarvier, Solovyov, Alexander, Greenbaum, Benjamin D., Chipuk, Jerry E., Celebi, Julide Tok
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6192859/
https://ncbi.nlm.nih.gov/pubmed/29665239
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pcmr.12704
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