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Affinity Maturation Is Impaired by Natural Killer Cell Suppression of Germinal Centers
Natural killer (NK) cells limit immunization-elicited follicular helper T cell and germinal center B cell responses. Rydyznski et al. link perforin-dependent functions of NK cells to a reduced frequency and quality of somatic hypermutation within antigen-specific B cells. Strategies targeting this N...
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| Publicado no: | Cell Rep |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6192537/ https://ncbi.nlm.nih.gov/pubmed/30257198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.08.075 |
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