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Molecular fine-tuning of affinity maturation in germinal centers
The development of high-affinity antibodies in response to infection is an iterative process in which B cells cycle between proliferation/somatic hypermutation and antigen-driven selection. These processes occur within specific regions of the secondary lymphoid structures known as germinal centers (...
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| Publicado no: | J Clin Invest |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Clinical Investigation
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4701570/ https://ncbi.nlm.nih.gov/pubmed/26657856 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI85627 |
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