Identification of a Structural Element in HIV-1 Gag Required for Virus Particle Assembly and Maturation

Late in the HIV-1 replication cycle, the viral structural protein Gag is targeted to virus assembly sites at the plasma membrane of infected cells. The capsid (CA) domain of Gag plays a critical role in the formation of the hexameric Gag lattice in the immature virion, and, during particle release,...

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發表在:mBio
Main Authors: Novikova, Mariia, Adams, Lucas J., Fontana, Juan, Gres, Anna T., Balasubramaniam, Muthukumar, Winkler, Dennis C., Kudchodkar, Sagar B., Soheilian, Ferri, Sarafianos, Stefan G., Steven, Alasdair C., Freed, Eric O.
格式: Artigo
語言:Inglês
出版: American Society for Microbiology 2018
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6191540/
https://ncbi.nlm.nih.gov/pubmed/30327442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.01567-18
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