The Role of WWP1-Gag Interaction and Gag Ubiquitination in Assembly and Release of Human T-Cell Leukemia Virus Type 1

The PPPY motif in the matrix (MA) domain of human T-cell leukemia virus type 1 (HTLV-1) Gag associates with WWP1, a member of the HECT domain containing family of E3 ubiquitin ligases. Mutation of the PPPY motif arrests particle assembly at an early stage and abolishes ubiquitination of MA. Similar...

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Bibliografiska uppgifter
Huvudupphovsmän: Heidecker, Gisela, Lloyd, Patricia A., Soheilian, Ferri, Nagashima, Kunio, Derse, David
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2007
Ämnen:
Structure and Assembly
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045422/
https://ncbi.nlm.nih.gov/pubmed/17609263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00642-07
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