The Role of WWP1-Gag Interaction and Gag Ubiquitination in Assembly and Release of Human T-Cell Leukemia Virus Type 1

The PPPY motif in the matrix (MA) domain of human T-cell leukemia virus type 1 (HTLV-1) Gag associates with WWP1, a member of the HECT domain containing family of E3 ubiquitin ligases. Mutation of the PPPY motif arrests particle assembly at an early stage and abolishes ubiquitination of MA. Similar...

Full description

Saved in:
Bibliographic Details
Main Authors: Heidecker, Gisela, Lloyd, Patricia A., Soheilian, Ferri, Nagashima, Kunio, Derse, David
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2007
Subjects:
Structure and Assembly
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2045422/
https://ncbi.nlm.nih.gov/pubmed/17609263
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00642-07
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items