Molecular mechanisms by which HERV-K Gag interferes with HIV-1 Gag assembly and particle infectivity

BACKGROUND: Human endogenous retroviruses (HERVs), the remnants of ancient retroviral infections, constitute approximately 8% of human genomic DNA. Since HERV-K Gag expression is induced by HIV-1 Tat in T cells, induced HERV-K proteins could affect HIV-1 replication. Indeed, previously we showed tha...

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Veröffentlicht in:Retrovirology
Hauptverfasser: Monde, Kazuaki, Terasawa, Hiromi, Nakano, Yusuke, Soheilian, Ferri, Nagashima, Kunio, Maeda, Yosuke, Ono, Akira
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
Schlagworte:
Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5406883/
https://ncbi.nlm.nih.gov/pubmed/28446240
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-017-0351-8
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