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Adiponectin modulates focal adhesion disassembly in activated hepatic stellate cells: implication for reversing hepatic fibrosis

Previous evidence indicates that adiponectin possesses antifibrogenic activity in inhibiting liver fibrosis. Therapeutic strategies, however, are limited by adiponectin quaternary structure and effective concentrations in circulation. Here we postulate a novel molecular mechanism, whereby adiponecti...

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Vydáno v:FASEB J
Hlavní autoři: Kumar, Pradeep, Smith, Tekla, Rahman, Khalidur, Mells, Jamie E., Thorn, Natalie E., Saxena, Neeraj K., Anania, Frank A.
Médium: Artigo
Jazyk:Inglês
Vydáno: Federation of American Societies for Experimental Biology 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6190967/
https://ncbi.nlm.nih.gov/pubmed/25154876
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.14-253229
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