Adiponectin inhibits hepatic stellate cell activation by targeting the PTEN/AKT pathway

Adiponectin inhibits hepatic stellate cell (HSC) activation and subsequent development of liver fibrosis via multiple mechanisms. Phosphatase and tensin homolog deletion 10 (PTEN) plays a crucial role in suppression of HSC activation, but its regulation by adiponectin is not fully understood. Here,...

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Bibliografske podrobnosti
izdano v:Biochim Biophys Acta Mol Basis Dis
Main Authors: Kumar, Pradeep, Raeman, Reben, Chopyk, Daniel M., Smith, Tekla, Verma, Kiran, Liu, Yunshan, Anania, Frank A.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6529190/
https://ncbi.nlm.nih.gov/pubmed/30293572
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbadis.2018.08.012
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